Occasionally, itching in the groin can result from chemical irritation (see vaginal itching, in women). Other causes include lichen simplex chronicus, eczema, and pubic lice.

Tinea cruris is a skin disorder that occurs almost exclusively in adult men. It can sometimes accompany athlete's foot (tinea pedis) and other tinea infections. The fungi that cause tinea infections, such as jock itch, thrive in warm, moist areas. Susceptibility to tinea infection is increased by friction, poor hygiene, prolonged wetness of the skin such as from sweating, and minor skin or nail injuries.

The body normally hosts a variety of microorganisms, including bacteria, mold-like fungi (dermatophytes) and yeast-like fungi (such as Candida). Some of these are useful to the body. Others can multiply rapidly and form infections.

Tinea infections are somewhat contagious and can be passed by direct contact with affected individuals or by contact with contaminated items such as clothing. Jock itch is usually localized to the groin and does not ordinarily involve the scrotum or penis. It is generally less severe than other tinea infections, but may be persistent. Jock itch may also be a cause of intractable pruritus ani (anal itching and discomfort).