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| Definition: | An acuterespiratory infection caused by the bacterium Legionella pneumophila, which can cause a broad spectrum of disease from mild cough and fever to a serious pneumonia.
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| Alternative Names: | Legionella pneumonia; Pontiac fever
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| Causes, incidence, and risk factors: | The bacteria have been found in water delivery systems and can survive in the warm, moist, air conditioning systems of large buildings including hospitals. The infection is transmitted through the respiratory route. Person to person spread has not been proven.
From the onset of symptoms, a worsening of the condition is typical during the first 4 to 6 days, with improvement starting in another 4 to 5 days. Most infection occurs in middle-aged or older people, although it has been reported in children. Typically, the disease is less severe in children.
Risk factors include cigarette smoking; underlying diseases such as renal failure, cancer, diabetes or chronic obstructive pulmonary disease; people with suppressed immune systems from chemotherapy, steroid medications or diseases such as cancer and leukemia; alcoholism; being middle-aged or elderly, and in chronically ventilated patients.
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Review Date: 7/17/2001
Reviewed By: Camille Kotton, M.D., Infectious Diseases Division, Massachusetts General Hospital and Brigham and Women's Hospital, Boston, MA. Review provided by VeriMed Healthcare Network.
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