DiseaseInjuryNutritionPoison
Special TopicSurgerySymptomsTest
2
4
5
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
OverviewSymptomsTreatmentPrevention

Primary hyperparathyroidism

Definition:
Primary hyperparathyroidism involves excessive production of parathyroid hormone caused by enlargement of one or more of the parathyroid glands.

Alternative Names:
Parathyroid-related hypercalcemia

Causes, incidence, and risk factors:

The parathyroid glands are located at the front and base of the neck at the 4 corners of the thyroid gland. The glands produce parathyroid hormone (PTH), which regulates calcium and phosphorus balance in the body.

In primary hyperparathyroidism, increased secretion of parathyroid hormone occurs because one or more of the glands have become enlarged. The effects of increased calcium are seen in several body systems including the skeletal, gastrointestinal, renal (kidney), muscular, and central nervous system.

The disease is most common in people over 60, but can also be seen in younger adults. Women are more likely to be affected than men. Radiation to the head and neck increases risk. Hyperparathyroidism in childhood is distinctly unusual.

Rarely, the disease is caused by parathyroid carcinoma.



Review Date: 9/1/2002
Reviewed By: Todd T. Brown, M.D., Division of Endocrinology and Metabolism, Johns Hopkins Hospital, Baltimore, MD. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

adam.com